The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
申请公布号
WO9400419(A1)
申请公布日期
1994.01.06
申请号
WO1993US05958
申请日期
1993.06.22
申请人
DEANA, ERMELINDA, S. +LF;MERCK & CO., INC.
发明人
DESOLMS, S., JANE;GRAHAM, SAMUEL, L.;SMITH, ROBERT, L.;DEANA, ALBERT, A. +DI
