摘要 |
<p>1,164,016. Anti - parasitic compositions. FARRENFABRIKEN BAYER A.G. 1 May, 1967 i [6 May, 1966; 3 Sept., 1966], No. 20013/ 67. Heading A5B. [Also in Division C2] Pharmaceutical preparations suitable for combatting internal parasites, e.g. cestodes, nematodes, trematodes (particularly liver flukes), contain as active ingredient compounds of the general formula I '(including salts thereof wherein R is a hydrogen atom or an acyl radical, R, and R 2 signify hydrogen, alkyly or alkoxy (R 2 may also be halogen), R 3 , R 4 and R; signify hydrogen. halogen, alkyl, hydroxy, alkoxy, nitro, haloalkyl, alkylmercapto or acyloxy and X and Y signify hydrogen, halogen or nitro and with the provisor that X and Y cannot in the same compound both be hydrogen and that when X is hydrogen Y can only be chlorine or bromine if each of the substituents R 3 , R 4 and R 5 is different from' the other two. Salts are those formed with bases such as sodium and potassium hydroxide ethanolamine, diethanolamine and piperazine. Alministration is orally, parenterally or subcutaneously, e.g. in the form of tablets, suppositories, pills, dragees, wrapped powders, cachets, sachets, capsules or ampoules.</p> |