USE OF AMINOTHIOPHENOLS IN THE TREATMENT OF DISORDERS ASSOCIATED WITH THE COMPLEMENT SYSTEM

摘要

A compound having an aromatic or heterocyclic ring with at least one primary amine group NH2 and at least one sulphydryl group SH directly attached to the ring, or a pharmaceutically acceptable salt thereof, for use in the treatment or prophylaxis of a complement related disorder or for reducing the risk of graft rejection. Complement related disorders include autoimmune diseases such as arthritis and rheumatism, myocardial infarction and tissue damage associated with radiotherapy. Examples for the compounds are 2-aminothiophenol and 4-aminothiophenol.