发明名称 TARGETED ACTIVATED SPECIES CYTOTOXICITY
摘要 <p>This invention comprises a method of treating animals, including humans, for conditions such as cancer by producing discrete site cytotoxic environment in an animal, including a human, by the steps of administering to the animal a therapeutically effective dosage of a prooxygenator-affixation element complex; in conjunction with, administering to the animal a therapeutically effective amount of an oxygen source substrate thus producing oxygen free radical species including superoxide at the site of binding. The present invention further comprises a prooxygenator-affixation element complex. In one embodiment the prooxygenator aspect is xanthine oxidase, the affixation element is a tumor specific antibody and the oxygen source substrate is xanthine.</p>
申请公布号 WO1993023080(A1) 申请公布日期 1993.11.25
申请号 US1993004582 申请日期 1993.05.13
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