摘要 |
<p>Novel platinum (IV) derivatives of general formula (I), method of preparation and tumour prevention compositions containing same. In general formula (I), R1 and R2 denote a polycyclic carbocycle or a mono, bi ou tricyclic heterocycle; X denotes chlorine or formula (II) or (III). Y denotes halo, -O-NO2, -O-R5, -O-CO-R5, -O-SO2-R5, -O-CO-NH-R5, -O-PO(OR5)2, or -O-P(OR5)2, (R5 = H, alkyl, alkenyl, alkynyl, cycloalkyl or aryl).</p> |