发明名称 ACTIVATION OF OLIGOMERIZING RECEPTORS BY USING FUSED RECEPTOR LIGANDS
摘要 The invention concerns a method for activating receptors selected from receptor tyrosine kinases, cytokine receptors and members of the nerve growth factor receptor superfamily. A conjugate comprising the direct fusion of at least two ligands capable of binding to the receptor(s) to be activated is contacted with the receptors, whereby the ligands bind their respective receptors inducing receptor oligomerization.
申请公布号 WO9323550(A2) 申请公布日期 1993.11.25
申请号 WO1993US04717 申请日期 1993.05.17
申请人 GENENTECH, INC. 发明人 GODOWSKI, PAUL, J.
分类号 C12N15/09;A61K47/48;C07K1/113;C07K14/475;C07K14/48;C07K14/485;C07K14/495;C07K14/505;C07K14/52;C07K14/53;C07K14/535;C07K14/54;C07K14/545;C07K14/55;C07K14/575;C07K14/61;C07K14/62;C07K14/65;C07K14/71;C07K14/715;C07K16/00;C07K19/00 主分类号 C12N15/09
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