发明名称 |
Sulfur-substituted mevinic acid derivatives |
摘要 |
<IMAGE> and pharmaceutically acceptable salts thereof possess activity as cell-selective HMG-CoA reductase inhibitors, thus making them useful as antihypercholesterolemic agents. In the above formula, X is hydrogen or -S(O)m-R1 and Y is hydrogen or S(O)n-R2, except that X and Y are not both hydrogen, or one of X and Y is -S-alkyl-SH and the other is hydrogen; <IMAGE> and the remaining symbols are as defined in the specification.
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申请公布号 |
US5264455(A) |
申请公布日期 |
1993.11.23 |
申请号 |
US19910724272 |
申请日期 |
1991.07.01 |
申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
VARMA, RAVI K.;SAUNDERS, JEFFREY O.;CHAO, SAM T.;GORDON, ERIC M.;SANTAFIANOS, DINOS P. |
分类号 |
C07C317/46;C07C323/61;C07C323/65;(IPC1-7):A61K31/35;A61K31/215;C07D339/00 |
主分类号 |
C07C317/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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