Neue Tricyclische Thiazolo- und Thiazino-Derivate und diese enthaltende Arzneimittel

摘要

The present invention relates to tricyclic thiazolo and thiazino derivatives of formula (I) in which A is a carbocyclic or heterocyclic ring, X may be an oxygen or sulphur atom or the group =NH, =N-C1-C6 alkyl or =S(O)2, R is an aliphatic radical with 1-9 C atoms, which may be substituted by phenyl, or a carbocyclic ring with 7-15 C atoms or a heterocyclic ring system, R<1> is a hydrogen atom, an aliphatic radical with 1-6 C atoms or C1-C6 alkoxy, C1-C6 alkylmercapto, C1-C6 alkylsulphinyl, C1-C6 alkylsulphonyl, amino, C1-C6 alkylamino, di-C1-C6 alkylamino, sulphonamido, C1-C6 alkoxycarbonyl, carboxy, halogen, hydroxy, nitro, cyano, azido, phenyl or benzyloxy, R<2>, R<3>, R<4> and R<5> may be hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, cyano, carboxy or C1-C6 alkoxycarbonyl and R<2> and R<4> are a further bond between the C atoms to which they are bonded, R<6> is hydrogen or C1-C6 alkyl, n is 0, 1 or 2 and m is 0 or 1, and their tautomers, enantiomers, diastereomers or physiological acceptable salts. The invention also relates to medicaments containing compounds of formula (I), especially for the treatment of viral infections.