| 摘要 |
<p>Compounds of general formula (II) wherein R3 is C¿1-35? hydrocarbyl group optionally substituted by one to five substituents, selected from halo, C1-6alkoxy, hydroxy, amino, and mono- or di-C1-4alkyl-amino; and either the dotted line represents a double bond between the 2 and 3 positions of the naphthyl ring; R?1 and R4¿ each represent = O; and R2 represents a group (a) wherein n is 2 or 3, R?6 and R7¿ which may be the same or different, each represent a hydrogen atom, a C¿1-6?alkyl group, optionally substituted by hydroxy, C1-6alkoxy or a group (b) wherein R?9¿ is a C¿1-6?alkyl group optionally substituted by an amino group optionally substituted by one or two alkyl groups, or R?6 and R7¿ may each be a group (c) wherein R8 is a C¿1-6?alkyl group, A is an oxygen atom or a group (d) wherein R?5¿ represents a hydrogen atom, a C¿1-6?alkyl group optionally substituted by hydroxy, C1-6 alkoxy or an amino group optionally substituted by one or two C1-6alkyl groups or R?5¿ is a group (e) wherein R10 is a C¿1-6?alkyl group or R?5¿ is a group (f) wherein p is 2 or 3 and R?11 and R12¿ are as hereinbefore defined for R?6 and R7¿ or, when m is 1 and n is 2 R5 may be linked to R6 so that (g) forms a piperazine ring; or the dotted line represents double bonds between the 1, 2 and 3, 4 positions of the naphthyl ring, and R?1, R2 and R4¿ each represent a group (h) (wherein n, A, R?6 and R7¿ are as hereinbefore defined); and physiologically acceptable salts thereof.</p> |
