| 摘要 |
<p>The present invention provides methods for inhibiting the binding of biologically active dimeric PDGF to cellular receptors. Using these methods, the proliferation of PDGF receptor-bearing cells and stenosis or restenosis can be inhibited. These methods employ a monomeric PDGF which is capable of binding to PDGF receptors and inhibiting the binding of dimeric PDGF. Methods are also provided for making the monomeric PDGF. The present invention further provides for native, biologically active monomeric PDGF.</p> |
