发明名称 |
Synthetic polypeptides as inhibitors of HIV-1. |
摘要 |
<p>Synthetic HIV-1-based polypeptides as well as methods for treating HIV-1 infections are provided herein. The polypeptides of the present invention have amino acid sequences substantially corresponding to a specified region of the HIV-1IIIB virus. The polypeptides of the present invention may be administered in effective amounts for preventing and treating HIV-1 infections. The polypeptides are useful for inhibiting the replication of the HIV-1 virus as well as HIV-1-mediated cytopathogenesis and cell fusion at levels which are within acceptable ranges of cytotoxicity. <IMAGE></p> |
申请公布号 |
EP0565164(A1) |
申请公布日期 |
1993.10.13 |
申请号 |
EP19930200863 |
申请日期 |
1993.03.25 |
申请人 |
THE NEW YORK BLOOD CENTER |
发明人 |
JIANG, SHIBO;LIN, KANG;NEURATH, A. ROBERT |
分类号 |
A61K38/00;A61K39/00;A61P31/12;C07K14/155;C07K14/16;C12N15/09;C12P21/02 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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