发明名称 |
Process for the preparation of substituted isoflavone derivative |
摘要 |
PCT No. PCT/HU90/00023 Sec. 371 Date Dec. 5, 1991 Sec. 102(e) Date Dec. 5, 1991 PCT Filed Apr. 6, 1990 PCT Pub. No. WO91/15483 PCT Pub. Date Oct. 17, 1991.The invention relates to a process for the preparation of pure isoflavone derivatives of the general formula (I), <IMAGE> (I) wherein R stands for hydrogen or isopropyl, R2 and R3 stand for hydrogen or C1-2 alkoxy by reacting a rezorcinol-derivative of the general formula (III) <IMAGE> (III) wherein R2 and R3 are as given above with ethyl-orthoformiate of the formula (IV) (C2H5O)3l CH(IV) in the presence of a base and optionally by alkylating the product.
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申请公布号 |
US5247102(A) |
申请公布日期 |
1993.09.21 |
申请号 |
US19910778927 |
申请日期 |
1991.12.05 |
申请人 |
CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. |
发明人 |
KALLAY, TAMAS;LANYI, GYOERGY;LEDNICZKY, LASZLO;IMREI, LAJOS;HOFFMANN, GYOERGY;SZILADI, MARIA;SOMFAI, EVA;MONTAY, TIBOR |
分类号 |
A61K31/35;A61K31/352;A61P3/02;A61P43/00;C07D311/36 |
主分类号 |
A61K31/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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