发明名称 INDOLE UREAS AS 5-HT1C RECEPTOR ANTOGONISTS
摘要 Indole ureas of formula (I) or a pharmaceutically acceptable salt thereof wherein: R1, R2 and R3 are independently hydrogen or C1-6alkyl; R4 is hydrogen, C1-6alkyl, halogen, hydroxy or NR8R9 where R8 and R9 are independently hydrogen or C1-6alkyl; R5 and R6 are independently hydrogen or C1-6alkyl; and R7 is hydrogen, C1-6alkyl or halogen; and wherein the urea moiety is attached at the 4-, 5- or 6- position of the indole ring. The compounds have 5HT1C receptor antagonist activity.
申请公布号 WO9318026(A1) 申请公布日期 1993.09.16
申请号 WO1992GB00381 申请日期 1992.03.04
申请人 BEECHAM GROUP PLC 发明人 FORBES, IAN, THOMSON;MARTIN, ROGER, THOMAS
分类号 C07D213/75;C07D401/12 主分类号 C07D213/75
代理机构 代理人
主权项
地址