发明名称 |
PROCESS FOR PREPARING 1-[/2S/-METHYL-3 -MERCAPTO-PROPIONYL]-PYRROLIDINE-/2S/-CARBOXYLIC ACID |
摘要 |
A process for preparing 1-¢/2S/-methyl-3-mercapto-propionyl!-pyrrolidine-/2S/-carboxylic acid The invention relates to a novel process for preparing 1-¢/2S/-methyl-3-mercaptopropionyl!-pyrrolidine-/2S/- -carboxylic acid of the formula I (I) in which 1-¢/2S/-methyl-3-thiocyanatopropionyl!-pyrrolidine- -/2S/-carboxylic acid of the formula II (II) is dissolved in an aqueous mineral acid, the solution obtained is diluted with water and the 1-¢/2S/-methyl-3-carbamoylthio-propionyl!-pyrrolidine-/2S/-carboxylic acid of the formula III (III) that forms is hydrolized with an aqueous solution of a base.
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申请公布号 |
CA2090921(A1) |
申请公布日期 |
1993.09.14 |
申请号 |
CA19932090921 |
申请日期 |
1993.03.03 |
申请人 |
EGIS GYOGYSZERGYAR RT. |
发明人 |
SCHNEIDER, GEZA;BLASKO, GABOR;KOVACS, AGNES;URMOES, GABRIELLA;DINNYES, ILMA;BECK, IVAN;JAKFALVI, ELEMER;DIETZ, ANDRAS |
分类号 |
A61K31/40;A61K31/401;A61P9/12;C07D207/16;(IPC1-7):C07D207/16 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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