发明名称 PYRIDYL AND PYRIMIDYL DERIVATIVES
摘要 The present invention concerns novel compounds of the formula: (I) wherein R1 and R2 are the same or different and selected from hydrogen and halogen: R3 and R4 are the same or different and selected from hydrogen and lower alkyl; n is 2 or 3; A is selected from the following pyrimidyl or pyridyl groups wherein R5 is selected from hydrogen, lower alkyl or halogen; R6 and R7 are the same or different and selected from hydrogen, halogen, lower alkyl, electron donor groups such as lower alkoxy or hydroxy, electron acceptor groups such as cyano, nitro, trifluoromethyl, COOR8, CONR9 or CO-B; wherein R8 is hydrogen or lower alkyl; R9 and R10 are the same or different and selected from hydrogen, lower alkyl and cycloalkyl; B is selected from wherein m is 1, 2, 3 or 4. R11 is selected from hydrogen or lower alkyl, and the pharmacologically active salts thereof. The new compounds can be used for treating mental disorders.
申请公布号 CA1321997(C) 申请公布日期 1993.09.07
申请号 CA19880563050 申请日期 1988.03.31
申请人 AKTIEBOLAGET LEO 发明人 FEX, TOMAS;OLSSON, KNUT G.;ABRAMO, AINA L.;CHRISTENSSON, ERIK G.;LUNDSTEDT, TORBJOERN E.
分类号 A61K31/495;A61K31/505;A61K31/535;A61K31/55;A61P25/00;A61P25/18;A61P25/20;A61P25/24;A61P25/26;C07D;C07D213/00;C07D213/72;C07D213/74;C07D213/76;C07D213/80;C07D213/81;C07D213/82;C07D213/85;C07D239/42;C07D401/00;C07D401/04;C07D401/06;C07D403/00;C07D403/04 主分类号 A61K31/495
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