| 摘要 |
2130443 9316708 PCTABS00025 A zinc depot for animals may be established through the introduction of a zinc substance exhibiting slow-release characteristics for the physiology of the animal, preferably via a non-digestive route. A fluid or paste-like composition, or a bolus, may be introduced through preferred routes such as into the bloodstream, intramuscularly, or subcutaneously. Preferred zinc substances include zinc organic salts and a specified range of preferred zinc inorganic compounds. Most exhibit a low aqueous solubility, less than or equal to 0.01 g/ml of H2O at 35 ·C. Other agents may enhance the effectiveness of the zinc substance, preferred agents including calcium, magnesium or selenium containing compounds or minerals, fatty acids, vegetable oils, and/or sulphur or sulphide compounds. The provision of a lasting zinc depot in an animal is useful for addressing zinc responsive disorders, both in a preventative and remedial sense. Examples of zinc-responsive disorders include facial eczema, fading elk's disease, mycotoxin poisoning, poisoning from alkaloid substances, disorders relating to phyto-oestrogen levels, and zinc deficiencies.
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