发明名称 |
BYSTANDER SUPPRESSION OF AUTOIMMUNE DISEASES |
摘要 |
The invention is directed to a method for treating autoimmune diseases in mammal s, the method comprising administering to the mammals an effective amount for treating the diseases of a bystander anti gen, the antigen eliciting the release of transforming growth factor beta (TGF-.beta.) at a locus within the body of the mammals wherei n T-cells contributing to autoimmune response are found to suppress the T-cells contributing to the disease. The invention is directed also to compositions comprising bystander antigens useful in the treatment of autoimmune diseases in mammals and to pharma ceutical formulations thereof.
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申请公布号 |
CA2117492(A1) |
申请公布日期 |
1993.09.02 |
申请号 |
CA19932117492 |
申请日期 |
1993.02.25 |
申请人 |
AUTOIMMUNE INC |
发明人 |
WEINER HOWARD L;MILLER ARIEL;ZHANG ZHENGRI;AL-SABBAGH AHMAD;HAFLER DAVID A |
分类号 |
A61K38/22;A61K38/00;A61K38/11;A61K38/17;A61K38/26;A61K38/28;A61K38/39;A61K39/00;A61P3/08;A61P3/10;A61P27/02;A61P29/00;A61P37/00;C07K14/47;(IPC1-7):A61K39/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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