发明名称 Bicyclic pyridine derivatives, process for their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them.
摘要 <p>The subject of the invention is the products of formula (I): &lt;IMAGE&gt; in which: one of A and B represents a nitrogen atom and the other represents a carbon atom, the dotted lines indicating that the pyridyl ring can be saturated or unsaturated, R represents an alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkyl-alkyl radical R1, R2, R3 and R4 represent: a) a radical -(CH2)m1-S(O)m2-X-R14 b) a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, sulphonyl, formyl, benzoyl, acyl or carboxyl radical, c) an alkyl, alkenyl, alkynyl, alkoxy, acyloxy, alkylthio, alkylsulphinyl or alkylsulphonyl radical, d) a cycloalkyl, aryl, arylalkyl, arylalkenyl, aryloxy, arylalkoxy, arylthio, arylsulphinyl or arylsulphonyl radical e) a radical &lt;IMAGE&gt; R5 represents a divalent alkylene radical or -C=O, Y represents the radical -Y1-B-Y2. These products have advantageous pharmacological properties which justify their use as medicaments.</p>
申请公布号 EP0556080(A1) 申请公布日期 1993.08.18
申请号 EP19930400194 申请日期 1993.01.27
申请人 ROUSSEL-UCLAF 发明人 CORBIER, ALAIN;FORTIN, MICHEL;GUILLAUME, JACQUES;HAESSLEIN, JEAN-LUC;VEVERT, JEAN-PAUL
分类号 A61K31/435;A61P9/10;A61P9/12;A61P11/06;A61P13/12;A61P15/00;A61P25/28;A61P27/06;A61P43/00;C07D471/04;C07F3/06 主分类号 A61K31/435
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