INHIBITION OF RESPIRATORY BURST USING POSTTRANSLATIONAL MODIFICATION INHIBITORS

摘要

2129235 9314749 PCTABS00024 The present invention relates to the use of posttranslational modification inhibitors, such as isoprenylation inhibitors, to inhibit activation of phagocyte NADPH oxidase and respiratory burst. Therapeutic medicaments and compositions containing various inhibitors, and methods of making and using same, are also disclosed.