发明名称 |
INTRACELLULAR ANTIGEN DISCOVERED IN SUBPOPULATION OF CD8 PLUS T LYMPHOCYTE AND MONOCLONAL ANTIBODY THEREAGAINST |
摘要 |
A 15 kd protein antigen is associated with cytoplasmic granules in cytolytic T lymphocytes and natural killer cells. Monoclonal antibodies immunologically reactive with the 15 kd protein and nucleic acid probes encoding polypeptides that are immunologically cross-reactive with the 15 kd protein can be used, e.g., to identify cytolytic lymphocytes in a sample. Cloned cDNA encoding the antigen can be used to produce the antigen. <IMAGE> |
申请公布号 |
JPH05184387(A) |
申请公布日期 |
1993.07.27 |
申请号 |
JP19900415435 |
申请日期 |
1990.12.28 |
申请人 |
DANA FARBER CANCER INST INC |
发明人 |
POORU JIEI ANDASON;MICHIERU SUTORUURI;SUTEYUAATO EFU SHIYUROSUMAN |
分类号 |
C07K16/00;C07K14/435;C07K14/47;C07K14/725;C07K16/18;C12N15/12;C12P21/08;C12Q1/68;C12R1/91;G01N33/49;G01N33/53;G01N33/577 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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