发明名称 |
PROCESS FOR THE PREPARATION OF NOVEL 2-THIENYL-OXYACETIC ACID DERIVATIVES |
摘要 |
Abstact The invention relates to a process for the preparation of novel 2-thienyloxyacetic acid derlvatives of the formula I I in which R denotes a phenyl or thienyl group which is optionally mono- or polysubstituted by halogen, trifluoromethyl or C1 - C4 alkyl, and of pharmaceutically usable salts thereof by oxidation of the corresponding sulfonamide alcohol of formula II with Ag2O and if appropriate conversion of the free acid into a salt. These compounds can be used for the treatment of thromboses, inflammations, high blood pressure, apoplexy and angina pectoris. |
申请公布号 |
CA1320492(C) |
申请公布日期 |
1993.07.20 |
申请号 |
CA19880562190 |
申请日期 |
1988.03.23 |
申请人 |
CL PHARMA AKTIENGESELLSCHAFT |
发明人 |
BINDER, DIETER;ROVENSZKY, FRANZ;FERBER, HUBERT P. |
分类号 |
C07D333/26;A61K31/38;A61K31/381;A61P7/02;A61P9/00;A61P11/00;A61P29/00;A61P43/00;C07D333/32 |
主分类号 |
C07D333/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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