摘要 |
PURPOSE:To obtain the subject cells useful for a therapeutic agent for infectious diseases, a diagnosticum for leukemia, having specific physical properties, being cells different from HL-60. CONSTITUTION:The objective cells having the following characteristics, (i) positive in butyrate esterase, (ii) positive in peroxidase, (iii) positive in cell surface marker OKM-1, (iv) negative in T cell receptor beta chain, immunoglobulin JH and KJ gene reconstitution, (v) having TGM-CSF dependence, (VI) expressing the same mRNA amount of myeloperoxidase as that of ML-60 and (VII) cells different from that of HL-60 by VNTR analysis. The microorganism of the cells is deposited as FERM P-12,663. |