发明名称 |
Targeted delivery of drugs to the lower gastrointestinal tract |
摘要 |
This invention relates to compositions for the treatment of certain diseases of the distal intestinal tract. Specifically, the invention relates to coated delivery vehicles such as nonporous microspheres, microscapsules, non-crosslinked porous beads or liposomes, for the sustained delivery of a therapeutically effective amount of an active agent. The composition is coated with a substance, e.g., a polysaccharide such as pectin, which is specifically attacked by intestinal bacteria to permit the release of the active agent in the distal intestinal tract, particularly the colon. |
申请公布号 |
WO9727843(A3) |
申请公布日期 |
1997.09.18 |
申请号 |
WO1997US00946 |
申请日期 |
1997.01.29 |
申请人 |
ADVANCED POLYMER SYSTEMS, INC. |
发明人 |
BERLINER, DAVID, L.;NACHT, SERGIO |
分类号 |
A61K9/127;A61K9/20;A61K9/28;A61K9/48;A61K9/52 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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