| 发明名称 |
TRANSFECTION OF LUNG VIA AEROSOLIZED TRANSGENE DELIVERY |
| 摘要 |
Methods and compositions for producing a mammal capable of expressing an exogenously supplied gene in cells of the airway are disclosed. Lipid carrier-nucleic acid complexes are prepared then delivered via aerosol to the lung airway. The invention provides a direct method for transforming pulmonary cells as a means for treating disorders of the lung as for providing a means for delivering substances systematically following expression in the lung. |
| 申请公布号 |
WO9312756(A2) |
申请公布日期 |
1993.07.08 |
| 申请号 |
WO1992US11008 |
申请日期 |
1992.12.17 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DEBS, ROBERT, J.;ZHU, NING |
| 分类号 |
A01K67/027;A61K9/00;A61K9/12;A61K9/127;A61K9/72;A61K31/711;A61K35/76;A61K38/00;A61K39/00;A61K47/16;A61K47/18;A61K47/28;A61K47/48;A61K48/00;A61P1/00;A61P11/00;A61P11/06;A61P31/04;A61P35/00;C07K14/47;C12N5/10;C12N15/09;C12N15/88;C12P21/02;C12R1/91 |
主分类号 |
A01K67/027 |
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