发明名称 |
SOLUBLE INTERLEUKIN-2 RECEPTOR AS AN INDICATOR OF MALIGNANCY AND A METHOD OF ASSAYING THE SAME |
摘要 |
<p>The present invention discloses a sandwich method and a kit for assaying interleukin-2 receptor (IL-2R) in a sample. The method comprises determining reactivity of said sample with a plurality of ligands, each said ligand having binding affinity for a specific site on the receptor, said site being different for each said ligand and distinct from interleukin-2 binding site on the receptor. The invention also discloses a method of detecting such disturbed or abnormal conditions in humans which release soluble IL-2R in the body fluid. <IMAGE></p> |
申请公布号 |
EP0202975(B1) |
申请公布日期 |
1993.06.30 |
申请号 |
EP19860400792 |
申请日期 |
1986.04.14 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE |
发明人 |
NELSON, DAVID LUTHER;BIDDISON, WILLIAM EDWARD;RUBIN, LAURENCE ANTHONY;GREENE, WARNER CRAIG;LEONARD, WARREN JAYE;YAUCHOAN, ROBERT |
分类号 |
G01N33/53;A61K35/14;A61K38/00;C07K14/005;C07K14/195;C07K14/705;C07K16/00;C07K16/28;C07K19/00;C12N5/10;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/577;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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