| 摘要 |
<p>The present invention provides a novel vaccine for protection of cattle against bovine respiratory syncytial virus (BRSV) infection. A vaccine composition includes an anti-idiotypic monoclonal antibody reactive against an idiotypic determinant of a primary antibody selected to interactably bind immune response evoking epitopes of BRSV, along with a pharmaceutically acceptable carrier for the anti-idiotypic monoclonal antibody. The vaccine composition is introduced into an animal to evoke an immune response in the animal that mimics the active immune response to BRSV proteins, effectively immunizing the animal.</p> |
