PROCESS FOR THE PREPARATION OF 3-ARYL ISOBUTANOLS

摘要

Process for the preparation of 3-aryl-isobutanols of the general formula I …… in which… R<1> and R<2> are hydrogen or an alkyl or cycloalkyl radical with up to 8 C atoms, preferably an alkyl radical with 1 to 4 C atoms,… which is characterised in that arylcarbinols of the general formula II …… are reacted with n-propanol in the presence of catalytic amounts of an alkali metal hydroxide or alkali metal oxide at 250 to 350 DEG C in a closed reaction vessel. …The process is particularly important for preparing 3-aryl-isobutanols of the formula I in which R<1> is an alkyl radical with 1 to 4 C atoms and R<2> is hydrogen. The p-methyl-, p-isopropyl- and p-tert.-butylphenylisobutanols obtained in this way in very high selectivity are valuable precursors for the fragrances jasmorange, cyclamenaldehyde and Lysmeral< TM > (Lilial< TM >) which are in high demand.