发明名称 |
Calcium-regulated promoter. |
摘要 |
<p>There is disclosed a new calcium-regulated promoter to be used for increasing production of extracellular enzymes, or heterologous polypeptides, a recombinant vector that includes the DNA sequence of the promoter operatively linked to a DNA encoding said enzyme or polypeptide and a host organism transformed with the recombinant vector that includes the promoter operatively linked to the DNA encoding said enzyme or polypeptide. The present invention further relates to Streptomyces expression systems and methods for expressing foreign DNA sequences in Streptomyces and for secreting to the surrounding medium polypeptides and proteins coded for by those foreign DNA sequences.</p> |
申请公布号 |
EP0546833(A2) |
申请公布日期 |
1993.06.16 |
申请号 |
EP19920311292 |
申请日期 |
1992.12.10 |
申请人 |
LABORATORIOS SERONO S.A. |
发明人 |
ORTEGA, ANTONIO DAZA;GIL, JOSE ANTONIO;GARCIA, TOMAS VIGAL;MARTIN, JUAN FRANCISCO |
分类号 |
C12N15/12;C12N1/21;C12N9/02;C12N9/12;C12N15/09;C12N15/63;C12N15/76;C12P21/00;C12P21/02;C12R1/465 |
主分类号 |
C12N15/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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