| 摘要 |
Compounds of formula (I) where A is a C1 or C2 alkylene chain optionally substituted by lower alkyl, Z is a bicyclic oxygen-containing radical (e.g. 2,3-dihydro-1,4-benzodioxin-5-yl), R is hydrogen or lower alkyl, R<1> is aryl or aryl(lower)alkyl and R<2> and R<3> are specified groups, and the pharmaceutically acceptable acid addition salts are novel. They are 5-HT1A-antagonists which may be used, for example, in treating anxiety.
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