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发明名称
2–胺基–5–羟基╳啶衍生物及其抑制白三烯素合成之功效
摘要
本发明揭示2-胺基及5-(羟基或烷氧基)啶及其衍生物,这些化合物是白三烯素合成的抑制剂,因此可用于治疗肺病、炎症、皮肤病,过敏病及心脏血管疾病。
申请公布号
TW206216
申请公布日期
1993.05.21
申请号
TW080102206
申请日期
1991.03.20
申请人
辉瑞股份有限公司
发明人
斐德律克.杰德生.沃可
分类号
A61K31/44;C07D213/74
主分类号
A61K31/44
代理机构
代理人
林敏生 台北巿南京东路二段一二五号七楼伟成第一大楼
主权项
1﹒一种如下式所示之化合物:其中R^1是苯基─C1─ C6─烷基,其中腹@ 茩f基可为卤素取代;或其药学上可接受的盐。 2﹒如申请专利范围第1项之化合物,其所述之化合 物是2─(3─对氯苯基 ─正丙基)胺基─5─羟基啶或2─(5─苯基─正 戊基)胺基─5─ 羟基啶。 3﹒一种用于治疗肺病,炎症,皮肤病,过敏病及心脏 血管疾病之药学组成物 ,其包含抑制白三烯素合成有效量之如申请专利范 围第1项之化合物及药 学上可接受之载体。
地址
美国
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