MATRIZE FUER BIOAKTIVE ZUSAMMENSETZUNG MIT DAUERVERABREICHUNG.

摘要

A sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of 5 to 95% by weight of a polyethylene glycol having a molecular weight of from about 1000 to about 20,000, and 95 to 5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid. Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding.