摘要 |
<p>Compounds of formula (I) wherein R1 and A are amino terminal groups: Z is O or N-R2; M is a dipeptide isostere; and D¿1? and D2 are optionally absent or amino acids; and pharmaceutically acceptable salts thereof, are potent inhibitors of the HIV-1 protease and are useful in the treatment of viral diseases such as Acquired Immune Deficiency Syndrome (AIDS).</p> |