发明名称 |
Squalene synthetase inhibitory composition and use thereof. |
摘要 |
<p>There is provided a squalene inhibitory composition containing 1,1-bisphosphonic acid compound, a lower alkyl ester thereof or a salt thereof, which is useful as a treating agent for hypercholesterolemia. There are also provided novel compounds having squalene synthetase inhibitory activity and a pharmaceutical composition for treating hypercholesterolemia containing a 1,1-bisphosphonic compound, a lower alkyl ester thereof or a salt thereof.</p> |
申请公布号 |
EP0541037(A2) |
申请公布日期 |
1993.05.12 |
申请号 |
EP19920118790 |
申请日期 |
1992.11.03 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
KITANO, KAZUAKI;SOHDA, TAKASHI;TOZAWA, RYUICHI;IKEDA, HITOSHI;ODA, TSUNEO |
分类号 |
A61K31/66;A61K31/665;A61K31/675;C07F9/38;C07F9/40;C07F9/58;C07F9/6506;C07F9/6512;C07F9/6524;C07F9/6539;C07F9/6541;C07F9/655;C07F9/6561 |
主分类号 |
A61K31/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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