| 摘要 |
<p>Disclosed is an essentially pure, recombinant, immunoreactive alpha-1 polypeptide subunit, or a portion thereof, of the human voltage-sensitive calcium channel protein expressed on human small cell lung carcinoma. Also disclosed is an isolated nucleic acid encoding this polypeptide and an expression vector containing such nucleic acid. In addition, methods are provided using this polypeptide for the detection of antibodies against calcium channel protein, and diagnosis of small cell lung carcinoma in a human subject, and for the detection and treatment of Lambert-Eaton Syndrome.</p> |
