摘要 |
Compounds have formula (I), in which R1 stands for alkyl or R5-substituted alkylene; R2 stands for alkyl; R3 stands for hydrogen, halogen, CHO (formyl), hydroxymethyl, nitro, amino or the substituent -CH2O-COR7; R4 stands for halogen or the substituent -A-B-R6; R5 stands for furyl, thienyl, tetrahydrofuryl, phenyl or phenyl substituted by two identical or different substituents from the group composed of halogen, alkyl, alkoxy, nitro, -NH-CO-NH2 (ureido), amino, alkylcarbonylamino and alkoxycarbonylamino; R7 stands for alkyl, alkoxy-alkyl, alkoxycarbonyl-alkyl or carboxy-alkyl; A stands for 0 (oxygen) or NH; B stands for a bond, -CH2- (methylene) or -CH2CH2- (1,2-ethylene); and n stands for the numbers 0 or 1. These new compounds are useful for preventing and treating gastro-intestinal disorders. |
申请人 |
BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH |
发明人 |
GRUNDLER, GERHARD;RAINER, GEORG;SCHAEFER, HARTMANN;SENN-BILFINGER, JOERG;SIMON, WOLFGANG-ALEXANDER;RIEDEL, RICHARD;POSTIUS, STEFAN;STURM, ERNST;HUBER, REINHARD;DAVID, MICHAEL |