发明名称 |
DIBENZ B,F 1,4 OXAZEPIN-11(10H)-ONES FOR MULTIDRUG RESISTANCE REVERSING AGENTS |
摘要 |
This invention relates to a compound of formula I <CHEM> wherein p is 1 to 3; R<1> and R<2> each are independently hydrogen or an acyl group R<6>CO-, in which R<6> is C1-6 alkyl, C3-7 cycloalkyl, C2-7 alkenyl, aryl or radical of the formula <CHEM> R<3> is hydrogen or chloro; R<4> and R<5> each are independently C1-6 alkyl. Compounds of formula I are useful for the reversal of multidrug resistance of cancer drugs. |
申请公布号 |
ZA9205287(B) |
申请公布日期 |
1993.04.28 |
申请号 |
ZA19920005287 |
申请日期 |
1992.07.15 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
IVO MONKOVIC;LOTTE WANG |
分类号 |
A61K31/55;A61K31/553;A61P35/00;A61P43/00;C07D267/20 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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