Styrene derivatives.

摘要

Styrene derivatives of the following general formula (I): <CHEM> ÄR<1>: cyano group, etc. R<2>: <CHEM> (Z is hydrogen atom, halogen atom, etc.), etc., R<3>: hydrogen atom, hydroxy group, etc., R4, R8: hydrogen atom, halogen atom, nitro group, etc., R5, R7: hydrogen atom, hydroxy group, halogen atom, cyano group, C<5> - C psi alkoxy group, C<5> - C psi alkyl group, etc., R6: hydroxy group, etc.Ü or pharmaceutically acceptable salts thereof. A pharmaceutical composition useful as anticancer agent, which comprises the above compound as an essential component, is also provided.