| 摘要 |
Compounds of the formula: <IMAGE> in which R1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, -NO2,-CN, 1-imidazolyl or 1,2,4-triazol-1-yl; Y is <IMAGE> -CH2-, -O-, -S-, or -SO2-; X is -CH= or -N=; R2 is hydrogen when n is 0, otherwise it is hydrogen or -OH; n is one of the integers 0, 1, 2, 3, 4, 5 or 6; A is <IMAGE> where R3 is alkylsulfonamido of 1 to 6 carbons atoms, arylsulfonamido of 6 to 10 carbon atoms, -NO2, -CN, 1-imidazolyl or 1,2,4-triazol-1-yl; or <IMAGE> where R4 is hydrogen or alkyl of 1 to 6 carbon atoms; with the provisos that; a) X is -CH= when Y is <IMAGE> -O- or -S- and when Y is <IMAGE> and R2 is -OH; b) X is -N= when A is <IMAGE> c) A is <IMAGE> when Y is -S- or -SO2- and X is -CH=, and their pharmaceutically acceptable salts are Class III antiarrhythmic agents.
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