| 发明名称 |
CARBAMATE ANALOGS OF THIAPHYSOVENINE, PHARMACEUTICAL COMPOSITIONS, AND METHOD FOR INHIBITING CHOLINESTERASES |
| 摘要 |
Substituted carbamates of tricyclic compounds which have a cyclic sulfer atom, provide highly potent and selective cholinergic agonist and blocking activity are useful as pharmaceutical agents. Cholinergic disease are treated with these compounds such as glaucoma, Myasthenia Gravis, Alzheimer's disease. Methods for inhibiting esterases, acetylcholinesterase and butyrylcholinesterase are also provided. |
| 申请公布号 |
WO9305779(A1) |
申请公布日期 |
1993.04.01 |
| 申请号 |
WO1992US07085 |
申请日期 |
1992.08.26 |
| 申请人 |
THE UNITED STATES OF AMERICA REPRESENTED BY THE SE |
发明人 |
BROSSI, ARNOLD;HE, XIAO-SHU;RAPOPORT, STANLEY, I.;GREIG, NIGEL, H.;BRZOSTOWSKA, MALGARZOTA |
| 分类号 |
A61K31/40;A61K31/407;A61P21/00;A61P21/04;A61P25/02;A61P25/28;A61P27/02;A61P27/06;A61P43/00;C07D495/04 |
主分类号 |
A61K31/40 |
| 代理机构 |
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代理人 |
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| 地址 |
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