Process for preparing enantiomerically pure imidazo¬4,5,1-jk -¬1,4 -benzodiazepin-2(1H)-thiones

摘要

Process for preparing enantiomerically pure imidazoÄ4,5,1-jkÜÄ1,4Übenzodiazepin-2(1H)-thiones of formula <CHEM> starting from 2,6-dihalo-3-nitrobenzyl derivatives (II) and suitably N-protected 1,2-diaminopropanes (III) <CHEM> Novel enantiomerically pure intermediates of formula (III) and (IV) prepared in the course of the present process.