| 摘要 |
Bicyclooctyl phosphines are disclosed having the formula: <IMAGE> (I) where R is C1 to C6 linear or branched alkyl, phenyl, substituted phenyl, halo, or C1 or C6 alkoxy; Ar is phenyl, substituted phenyl, naphthyl or substituted naphthyl; and x is 0 or 1. These phosphines are treated with ruthenium compounds to form a complex of the formula RuxHyClz (anthraphos-m)2 (S)p, where S is a tertiary amine; and when y is 0, then x is 2, z is 4 and p is 1; and when y is 1, then x is 1, z is 1 and p is 0; where anthraphos-m is: <IMAGE> (I) where R is C1 to C6 linear or branched alkyl, phenyl, substituted phenyl, C1 to C6 linear or branched alkoxy or halo; Ar is phenyl or substituted phenyl or naphthyl or substituted naphthyl; and m is 0 or 1. The complex is useful in a process for the asymmetric reduction of olefinic carboxylic acids of the formula: <IMAGE> where R1 and R2 are the same or different and are hydrogen, alkyl, cycloalkyl or haloalkyl; and Ar' is aryl or substituted aryl.
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