发明名称 Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation.
摘要 <p>Treatment or prevention of myointimal proliferation in atherosclerosis, restenosis induced by angioplasty or vascular reconstructive surgery, glomerulonephritis, glomerulosclerosis or other diseases involving vascular cell proliferation, with a natriuretic peptide or a neutral endopeptidase inhibitor such as N-[N-[(L)-[1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]carbonyl]-2-phen ylethyl]-L-phenylalanyl]- beta -alanine and N-[2-mercaptomethyl-3-(2-methylphenyl)propionyl]-methionine, or with a neutral endopeptidase inhibitor in combination with a natriuretic peptide or an angiotensin converting enzyme inhibitor are disclosed.</p>
申请公布号 EP0533084(A1) 申请公布日期 1993.03.24
申请号 EP19920115681 申请日期 1992.09.14
申请人 SCHERING CORPORATION 发明人 DAVIS, HARRY R.;SYBERTZ, EDMUND J.
分类号 A61K38/22;A61K38/55;A61P9/00;A61P43/00 主分类号 A61K38/22
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