发明名称 IMIDAZOLIDYL MACROLIDES
摘要 Imidazolidyl macrolides of general structural formula (I) have been prepared from suitable precursors by alkylation and/ or arylation at C-3" and/or C-4" of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases; infectious diseases, the preventio n of rejection of foreign organ transplants and/or re- lated afflictions, diseases and illnesses.
申请公布号 CA2116674(A1) 申请公布日期 1993.03.18
申请号 CA19922116674 申请日期 1992.09.02
申请人 MERCK & CO INC 发明人 GOULET MARK;SINCLAIR PETER J;WYVRATT MATTHEW J;WONG FREDERICK
分类号 C07H19/01;A61K;A61K31/395;A61K31/4178;A61K31/4184;A61K31/422;A61K31/423;A61K31/427;A61K31/428;A61K31/435;A61K31/436;A61K31/70;A61K31/7056;A61P37/06;C07D;C07D498/12;C07D498/18;C07H7/06;C07H15/04;C07H19/02;(IPC1-7):C07H19/01 主分类号 C07H19/01
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