N-£1-(2-PHENYLETHYL)-4-PIPERIDINYL|THIOPROPIONANILIDE AND MALEATE THEREOF

摘要

N-(1-(2-phenylethyl)-4-piperidinyl)thiopropionanilide and its maleate. In the form of this salt the abovementioned substance has an intensive analgesic effect like morphine. The substance according to the invention is obtainable by the reaction of N-(1-(2-phenylethyl)-4-piperidinyl)propionanilide with phosphorus(V) sulphide in boiling pyridine. As a base the substance is crystalline and by neutralising the base with maleic acid crystalline hydrogen maleate is obtained.