摘要 |
The present invention relates to a receptor for advanced glycosylation endproducts that may be derived from rat liver membranes or mesangial cells, and that specifically comprises certain proteins determined to possess molecular masses of about 90 kD, 60 kD, 50 kD, 40 kD and 30-35 kD, respectively, as assessed by migration during SDS-PAGE. Partial N-terminal sequences have been determined and diagnostic and therapeutic agents, compositions and methods are proposed. |