SEPARATION TECHNIQUE FOR A MIXTURE OF (6RS)-DIASTEREOISOMERS OF AN AMMONIUM SALT OF N5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID INTO SINGLE (6R) AND (6S)-DIASTEREOISOMERS

摘要

There are described ammonium salts of N5-methyl-5,6,7,8-tetrahydrofolic acid as well as processes for their preparation. These ammonium salts may be separated into the single (6R) and (6S)-diastereoisomers. The separated diastereoisomers may be transformed into the corresponding alkali metal or alkaline earth metal salts.