METHOD FOR PREPARING A LIPOPROTEIN MODIFIED BY THE INCORPORATION OF A LIPOPHILIC ACTIVE SUBSTANCE

摘要

PCT No. PCT/FR91/00573 Sec. 371 Date May 6, 1992 Sec. 102(e) Date May 6, 1992 PCT Filed Jul. 12, 1991 PCT Pub. No. WO92/00761 PCT Pub. Date Jan. 23, 1992.Method of preparing a lipoprotein modified by incorporation of at least one lipophilic active substance other than a triglyceride, characterized by incorporation of said active substance into an emulsion of a lipid phase in a continuous aqueous phase, by adding to the emulsion, with stirring, an original lipoprotein and at least one lipid transfer protein, allowing the mixture to incubate, and, using known methods, isolating the lipoprotein into which the active substance is incorporated; a lipoprotein thus obtained, and pharmaceutical or cosmetic composition containing such a modified lipoprotein.