摘要 |
<p>A method of protecting 3-isothiazolones of the formula: <CHEM> wherein Y is (C1-C18)alkyl or (C3-C12)cycloalkyl each optionally substituted with one or more of hydroxy, halo, cyano, alkylamino, dialkylamine, arylamino, carboxy, carbalkoxy, alkoxy, aryloxy, alkylthio, arylthio, haloalkoxy, cycloaklylamino, carbamoxy, or isothiazolonyl; an unsubstituted or halo-substituted (C2-C8) alkenyl or alkynyl; a (C7-C10)aralkyl optionally substituted with one or more of halogen, (C1-C4)alkyl or (C1-C4)alkoxy; and an aryl optionally substituted with one or more of halogen, nitro, (C1-C4)alkyl, (C1-C4)alkyl-acylamino, carb(C1-C4)alkoxy or sulfamyl; and R and R<1> is each independently H, halogen (C1-C4) alkyl, (C4-C8) cycloalkyl or joined together to form a phenyl; comprising incorporating therewith an effective amount of a nitrogen-containing, sulphur-free compound, capable of reversibly associating with said isothiazolone.</p> |