2-Piperidinecarboxylic acid derivative, oncogene suppressor and agent for obtaining revertants.
摘要
<p>A novel 2-piperidinecarboxylic acid derivative represented by the formula: <CHEM> wherein X represents an oxygen atom, a sulfur atom or a nitrogen atom to which a hydrogen atom is bound; and * represents that the configuration of the carbon atom binding to the carboxyl group is (S), (R) or a mixture of (S) and (R); and a pharmaceutically acceptable salt thereof which exerts an antitumor effect over a wide range of tumor cells.</p>
申请公布号
EP0529655(A1)
申请公布日期
1993.03.03
申请号
EP19920114749
申请日期
1992.08.28
申请人
MEIJI SEIKA KAISHA LTD.
发明人
IKONOGI, TSUNEO;MAKABE, OSAMU;YAMAMOTO, YUICHI;ITOH, OSAMU;TSURUOKA, TSUTOMU;USUI, TAKAYUKI;SHIBAHARA, SEIJI;NAGAOKA, KOZO;INOUYE, SHIGEHARU;OKADA, NOBUKO, NATIONAL CANCER CENTER RES.INST.;NISHIMURA, SUSUMU