发明名称 |
LATERAL FLOW, NON-BIBULOUS MEMBRANE PROTOCOLS |
摘要 |
A method and apparatus for conducting specific binding pair assays, such as immunoassays, is described. A porous membrane capable of non-bibulous lateral flow is used as assay substrate; a member of the binding pair is affixed in an indicator zone defined in the substrate. The sample is applied at a position distant from the indicator zone and permitted to flow laterally through the zone; any analyte in the sample is complexed by the affixed specific binding member, and detected. A novel method of detection employs entrapment of observable particle in the complex. Blood is a particularly preferred sample as the red blood cells can be used as the observable particles for detection of the complex. |
申请公布号 |
CA1313616(C) |
申请公布日期 |
1993.02.16 |
申请号 |
CA19880568070 |
申请日期 |
1988.05.30 |
申请人 |
QUIDEL |
发明人 |
SARGEANT, ROBERT B.;KHALIL, MOHAMMED M.;KATZ, DAVID H.;EISINGER, ROBERT W. |
分类号 |
G01N33/543;G01N33/558;G01N37/00 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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